A modified in situ Suzuki cross-coupling of haloarenes for the preparation of C 2-symmetric biaryls

NG Andersen, SP Maddaford…

Index: Andersen, Neil G.; Maddaford, Shawn P.; Keay, Brian A. Journal of Organic Chemistry, 1996 , vol. 61, # 26 p. 9556 - 9559

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Citation Number: 72

Abstract

Palladium-catalyzed cross-coupling between aryl boronic acids and haloarenes or aryl triflates has been shown to be a versatile method for the preparation of biaryls. 1 The original procedure developed by Suzuki2 has achieved widespread popularity in organic synthesis since it is compatible with a large variety of functional groups and the conditions tolerate aqueous reaction media. Moreover, the inorganic byproduct of the reaction is ...