Australian Journal of Chemistry

Organophosphorus compounds. VIII. Diphenylphosphinothioic acid derivatives as reagents for proteins

RA Spence, JM Swan, SHB Wright

Index: Spence,R.A. et al. Australian Journal of Chemistry, 1969 , vol. 22, p. 2359 - 2370

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Abstract

Abstract Esters and other derivatives of diphenylphosphinothioic acids are examined as potential agents for the radioactive labelling of immunoglobulins and other proteins. Syntheses, model reactions with amines, and mass spectra of the organo-phosphorus compounds are discussed. The labelling of immunoglobulins by reaction with [32 P] diphenylphosphinothioic chloride, with [32 P] diphenylphosphinothioic isothiocyanate, ...