A novel synthesis of nucleoside 5′-triphosphates
NC Mishra, AD Broom
Index: Mishra, Nrusingha C.; Broom, Arthur D. Journal of the Chemical Society, Chemical Communications, 1991 , # 18 p. 1276 - 1277
Full Text: HTML
Citation Number: 30
Abstract
Facile syntheses of ribonucleoside 5′-triphosphates have been accomplished in good yield (> 60%) in a one-pot reaction of unprotected nucleosides with phosphoryl chloride followed by treatment of the resulting phosphorodichloridate with tri-n-butylammonium phosphate in the presence of dimethylformamide.
Related Articles:
AP (V)–N Activation Strategy for the Synthesis of Nucleoside Polyphosphates
[Sun, Qi; Gong, Shanshan; Sun, Jian; Liu, Si; Xiao, Qiang; Pu, Shouzhi Journal of Organic Chemistry, 2013 , vol. 78, # 17 p. 8417 - 8426]