Ratiometric fluorescent sensor based on inhibition of resonance for detection of cadmium in aqueous solution and living cells

L Xue, G Li, Q Liu, H Wang, C Liu, X Ding, S He…

Index: Xue, Lin; Li, Guoping; Liu, Qing; Wang, Huanhuan; Liu, Chun; Ding, Xunlei; He, Shenggui; Jiang, Hua Inorganic Chemistry, 2011 , vol. 50, # 8 p. 3680 - 3690

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Citation Number: 77

Abstract

Under physiological conditions, DQCd1 can be protonated and result in an essential resonance process. Upon binding of Cd2+, the resonance process of the protonated DQCd1 was turned off, and this led to a ratiometric signal output for sensing Cd2+. The laser scanning confocal microscopy experiments reveal that cell-permeable DQCd1 can visualize the changes of intracellular Cd2+ via dual-emission ratiometry.