Chiral cyclic olefins. 1. Synthesis, resolution, and stereochemistry of 5-hydroxy-10-alkyl-. DELTA. 1 (9)-2-octalones

GR Newkome, LC Roach…

Index: Newkome,G.R. et al. Journal of Organic Chemistry, 1972 , vol. 37, p. 2098 - 2101

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Citation Number: 12

Abstract

In connection with a current project dealing with the synthesis of optically active cyclic olefins, lb it became necessary to synthesize, resolve, and determine the absolute configuration of the title compounds before proceeding with this project. Syntheses of chiral steroid synthetic intermediates, such as 1 and 2, have been accomplished by resol~ tion,~-~ microbiological reductions,'and most recently by “chiral induction.*” In view of the various ...