Journal of heterocyclic chemistry

Synthesis of a novel indolobenzodiazepine

NP Peet, S Sunder

Index: Peet, Norton P.; Sunder, Shyam Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1355 - 1357

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Citation Number: 3

Abstract

Abstract 2-[(5-Methyl-1, 3, 4-oxadiazol-2-yl) methyl] benzenamine (15) was prepared in four steps from o-nitrophenyl-acetic acid, and treated with triethyl orthoformate in an attempt to prepare an oxadiazolobenzodiazepine. However, the resulting product was 13-(5-methyl-1, 3, 4-oxadiazol-2-yl)-5H-indolo [2, 1-b][1, 3] benzodiazepine monohydrate (16). Indolobenzodiazepine 16 is the first reported member of a novel ring system. Interesting ...