Synthetic Communications

One-Pot, Two-Step Direct Conversion of Alkenes to Amines Through Tandem Ozonolysis and Ammonia-Borane in Water

V Tyagi, AK Gupta

Index: Tyagi, Vipin; Gupta, Ashok Kumar Synthetic Communications, 2014 , vol. 44, # 4 p. 493 - 499

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Citation Number: 3

Abstract

An efficient, one-pot, two-step reductive amination of alkenes through tandem ozonolysis using ammonia-borane as a reducing agent is described. The reaction has been carried out in water. This is a highly efficient and mild procedure that is applicable to a wide variety of amine substrates. In particular, this is the first successful manifestation that this type of reaction can be carried out in water with ammonia-borane. ... [Supplementary materials are available ...

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