Investigating biological activity spectrum for novel styrylquinazoline analogues

…, M Pesko, J Carroll, K Kralova, M Vejsova, J O'Mahony…

Index: Jampilek, Josef; Musiol, Robert; Finster, Jacek; Pesko, Matus; Carroll, James; Kralova, Katarina; Vejsova, Marcela; O'Mahony, Jim; Coffey, Aidan; Dohnal, Jiri; Polanski, Jaroslaw Molecules, 2009 , vol. 14, # 10 p. 4246 - 4265

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Citation Number: 33

Abstract

Abstract In this study, series of ring-substituted 2-styrylquinazolin-4 (3H)-one and 4-chloro-2- styrylquinazoline derivatives were prepared. The syntheses of the discussed compounds are presented. The compounds were analyzed by RP-HPLC to determine lipophilicity. They were tested for their inhibitory activity on photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. Primary in vitro screening of the synthesized ...