Bulletin of the Chemical Society of Japan

A Simplified Method for the Preparation of N-Acetylphenylalanines

T Okuda, Y Fujii

Index: Okuda; Fujii Bulletin of the Chemical Society of Japan, 1957 , vol. 30, p. 698

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Citation Number: 6

Abstract

A simple and practical procedure is described of preparing N-acetylphenylalanines by hydrogenation of the corresponding unsaturated azlactones in an aqueous sodium hydroxide solution with Raney nickel under pressure. By this method N-acetyl derivatives of phenylalanine, p-methylphenylalanine, p-methoxyphenylalanine and 3, 4- methylenedioxyphenylalanine were synthesized in good yield.

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