Tetrahedron

Etude d'un schema de synthese peptidique intramoleculaire a l'aide de derives du phosphore tetraedrique

M Mulliez

Index: Mulliez, M. Tetrahedron, 1981 , vol. 37, p. 2027 - 2041

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Citation Number: 11

Abstract

A new scheme of repetitive and controlled peptide synthesis offers two advantages compared to the usual methods of synthesis: two steps only are used for the prolongation of a peptide chain with an aminoacid residue and the risk of racemisation is minimized. The two postulated steps are verified particularly by the rearrangement, in an alkaline alcoholic medium, of phosphordiamides 1 incorporating one amino-acid residue, leading to the ...