Synthesis of C-nucleosides. Part 14. 5 (3)-Glycosyl-1, 2, 4-triazole-3 (5) carboxamides as analogues of ribavirin

T Huynh-Dinh, J Igolen, E Bisagni…

Index: Huynh-Dinh; Igolen; Bisagni; Marquet; Civier Journal of the Chemical Society. Perkin transactions 1, 1977 , # 7 p. 761 - 764

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Citation Number: 24

Abstract

Alkyl thioimidates react with hydrazides of methyl hydrogen oxalate and oxamic acid to yield methyl 1, 2, 4-triazole 3 (5)-carboxylates and-carboxamides. Ribo-, deoxyribo-and arabino- C-nucleoside analogues of ribavirin have been prepared and their structures established by nmr and mass spectrometry.

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