N??Alkylation of imides using phase transfer catalysts under solvent??free conditions

J Jaśkowska, P Kowalski

Index: Jaskowska, Jolanta; Kowalski, Piotr Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 5 p. 1371 - 1375

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Citation Number: 10

Abstract

Imides are important organic compounds, which have been widely used in biology [1]. They are also useful as intermediates in organic synthesis [2] and polymer chemistry [3]. N-Alkyl derivatives of imides find broad use in pharmacology. Some N-alkyl phthalimides have been applied as antipsychotic [4] and anti-inflammatory [5] agents. Arylpiperazinylalkyl derivatives of phthalimide [6-8], succinimide [6], saccharin [8] and 1, 3-benzoxazine-2, 4-dione [9] are ...