Journal of the American Chemical Society

Chloro and fluoro compounds related to adrenalone

HL Hansen

Index: Hansen Journal of the American Chemical Society, 1937 , vol. 59, p. 280

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Citation Number: 9

Abstract

The influence of nuclear chlorine and bromine on the chemical and pharmacological properties of amines of the pressor type has engaged the attention of several investigators. Zeynek'prepared both 3, 5-dichloro-and 3, 5-dibromotyramine. Glynn and Linnel12 prepared w-amin0-3~ 4-dichloroacetophenone as well as 3, 4-dichlorophenyl-P-aminoethanol and reported for the latter substance a pressor effect much smaller than that of epinephrine but ...