Transition metal-free 1, 3-dimethylimidazolium hydrogen carbonate catalyzed hydration of organonitriles to amides

PK Verma, U Sharma, M Bala, N Kumar, B Singh

Index: Verma, Praveen Kumar; Sharma, Upendra; Bala, Manju; Kumar, Neeraj; Singh, Bikram RSC Advances, 2013 , vol. 3, # 3 p. 895 - 899

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Citation Number: 7

Abstract

Many efficient catalytic methods based on enzymes 6 and transition metals (Ni, Pt, Rh, Ir, Mo, Au, Cu, Co, Pd, Ru, Ag) 7 have been developed for hydration of nitriles. However, the necessity of special handling of microorganisms (enzymes), difficulty in catalyst/product separation, high temperature/pressure and use of costly transition metal complexes limit the scope of these methods. Hence, the development of metal free methods is highly desirable.