Aldehydes from dihydro-1, 3-oxazines. III. Synthesis of cycloalkanecarboxaldehydes

AI Meyers, HW Adickes, IR Politzer…

Index: Meyers,A.I. et al. Journal of the American Chemical Society, 1969 , vol. 91, p. 765 - 767

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Citation Number: 13

Abstract

(2) Columbia Organic Chemicals, Columbia, SC(3) AI Meyers and A. Nabeya, Chem. Commun., 1163 (1967).(4) The anions 2 (A= H, Ph) were generated as described in ref 1. whereas 2 (A= C02Et) was quantitatively formed using sodium hydride in THF. yield (based on the dihalide). 5 The low yield of the 2-cyclobutyloxazine (entry 2) was due to the competing cyclization of 3 (A= H) to the quaternary salt 7 (X= Br). The latter was extremely ...