The synthesis of phenyl-substituted triazole analogs of histamine
JC Sheehan, CA Robinson
Index: Sheehan; Robinson Journal of the American Chemical Society, 1951 , vol. 73, p. 1207,1209
Full Text: HTML
Citation Number: 33
Abstract
Based on the antihistaminic activity shown by the triazole analog of histamine, which was previously reported2 it appeared of interest to extend this investigation to some related compounds. A possible mode of action of antihistaminics is by an antagonism in which a blocking molecule adheres to the cell surface and not only prevents histamine from reaching its site of action but also, by the screening effect of large blocking groups, inactivates ...
Related Articles:
Per (2-thienyl) pyridines: Synthesis and Properties
[Potratz, Stefanie; Mishra, Amaresh; Baeuerle, Peter Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 683 - 692]
[Alonso, Francisco; Moglie, Yanina; Radivoy, Gabriel; Yus, Miguel Advanced Synthesis and Catalysis, 2010 , vol. 352, # 18 p. 3208 - 3214]
Per (2-thienyl) pyridines: Synthesis and Properties
[Potratz, Stefanie; Mishra, Amaresh; Baeuerle, Peter Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 683 - 692]
[Bedford, C. D.; Bruckmann, E. M.; Smith, P. A. S. Journal of Organic Chemistry, 1981 , vol. 46, # 4 p. 679 - 686]
[Oetvoes, Sandor B.; Mandity, Istvan M.; Kiss, Lorand; Fueloep, Ferenc Chemistry - An Asian Journal, 2013 , vol. 8, # 4 p. 800 - 808]