Synthesis of a naphthalene endoperoxide as a source of 18O-labeled singlet oxygen for mechanistic studies

GR Martinez, JL Ravanat, MHG Medeiros…

Index: Martinez; Ravanat; Medeiros; Cadet; Di Mascio Journal of the American Chemical Society, 2000 , vol. 122, # 41 p. 10212 - 10213

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Citation Number: 83

Abstract

Singlet oxygen (1O2) exhibits a substantial reactivity toward electron-rich organic molecules, leading to the formation of allylic hydroperoxides, dioxetanes, or endoperoxides. 1 Singlet oxygen has been shown to be generated in biological systems. 2 As possible biological sources of 1O2, we may mention enzymatic processes catalyzed by peroxidases or oxygenases, 3 reactions of hydrogen peroxide with hypochlorite4 or peroxynitrite, 5 ...