Australian Journal of Chemistry

Hydropyrimidines. V. Hexahydropyrimidines. The reaction of aldehydes and ketones with 1, 3-diaminopropanes

RF Evans

Index: Evans,R.F. Australian Journal of Chemistry, 1967 , vol. 20, p. 1643 - 1661

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Citation Number: 51

Abstract

Abstract Hexahydropyrimidine and some N-alkylated derivatives have been obtained from the reaction of the corresponding trimethylenediamine or its monoprotonated salt with formaldehyde. A variety of spectroscopic evidence supports a cyclic structure for these compounds in preference to a tautomeric open-chain form. The chemical behaviour of hexahydropyrimidine is explicable in terms of a cyclic di-secondary amine structure. The ...