Micelles catalyzed chemoselective synthesis 'in water'and biological evaluation of oxygen containing hetero-1, 4-naphthoquinones as potential antifungal agents

VK Tandon, HK Maurya, NN Mishra…

Index: Tandon, Vishnu K.; Maurya, Hardesh K.; Mishra, Nripendra N.; Shukla, Praveen K. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 21 p. 6398 - 6403

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Citation Number: 13

Abstract

Various oxygen containing 1, 4-naphthoquinone derivatives have been synthesized chemoselectively by an economical, viable green methodology approach using water as solvent with or without surfactants such as Triton X-100, SDS, LD (laundry detergent), and TBAB, a phase transfer catalyst and evaluated for their in vitro antifungal and antibacterial activity. The antifungal profile of 3, 4a, 4b, and 6 indicated that compounds 3a, 3b, 4b, 6a, ...