Design and Synthesis of Urea??Linked Aromatic Oligomers—A Route Towards Convoluted Foldamers

JJ Mousseau, L Xing, N Tang…

Index: Mousseau, James J.; Xing, Liyan; Tang, Nathalie; Cuccia, Louis A. Chemistry - A European Journal, 2009 , vol. 15, # 39 p. 10030 - 10038

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Citation Number: 18

Abstract

Abstract Herein we report the design and synthesis of crescent-shaped and helical urea- based foldamers, the curvature of which is controlled by varying the constituent building blocks and their connectivity. These oligomers are comprised of two, three or five alternating aromatic heterocycles (pyridazine, pyrimidine or pyrazine) and methyl-substituted aromatic carbocycles (tolyl, o-xylyl or m-xylyl) connected together through urea linkages. A crescent ...