Facile synthesis of glycol metabolites of phenethylamine drugs1

MH Holshouser, M Kolb

Index: Holshouser; Kolb Journal of Pharmaceutical Sciences, 1986 , vol. 75, # 6 p. 619 - 621

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Citation Number: 15

Abstract

Abstract High yields of potential glycol metabolites of p-synephrine, epinephrine, octopamine, and normacromerine can be obtained from the readily available monosubstituted and disubstituted acetophenones. The general procedure involves alpha-