5-Aryl-4-carboxamide-1, 3-oxazoles: potent and selective GSK-3 inhibitors

G Gentile, G Merlo, A Pozzan, G Bernasconi…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 5 p. 1989 - 1994

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Citation Number: 30

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... a Department of Medicinal Chemistry, Neuroscience Centre of Excellence of Drug Discovery ... However, one concern about compound 1 was its unfavourable physico-chemical properties, and potential low CNS permeability. ...