Cyanation of allylic carbonates and acetates using trimethylsilyl cyanide catalyzed by palladium complex

Y Tsuji, N Yamada, S Tanaka

Index: Tsuji, Yasushi; Yamada, Naoaki; Tanaka, Shinsuke Journal of Organic Chemistry, 1993 , vol. 58, # 1 p. 16 - 17

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Citation Number: 43

Abstract

Summary: Allylic carbonates and acetates are cyanated with trimethylsilyl cyanide in the presence of a catalytic amount (5 mol % based on the allylic substrates) of Pd- (PPh3)4 or Pd(CO)(PPh& in THF under reflux to afford &y-unsaturated nitriles in high yields. ... Palladium-catalyzed transformations of allylic acetates 1 and carbonates 2 have received much attention as methods of organic synthesis.' In the presence of palla- dium catalysts, these allylic substrates provide ?r-allyl ...