Tetrahedron letters

Diethyl (N-Methoxy-N-methylcarbamoylmethyl) phosphonate-A Useful Emmons-Horner Wittig Reagent

DF Netz, JL Seidel

Index: Netz, David F.; Seidel, Jimmy L. Tetrahedron Letters, 1992 , vol. 33, # 15 p. 1957 - 1958

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Citation Number: 24

Abstract

Abstract Diethy (N-methoxy-N-methylcarbamoylmethyl) phosphonate (1) is easily prepared by heating 2-chloro-N-methoxy-N-methylethanamide and triethylphosphite. Reagent 1 is useful for converting aldehydes and ketones into compounds containing an α, β-unsaturated N-methoxy-N-methylamide group with high E selectivity.