Conformational Preference in Bis (porphyrin) Tweezer Complexes: A Versatile Chirality Sensor for α??Chiral Carboxylic Acids

M Tanasova, B Borhan

Index: Tanasova, Marina; Borhan, Babak European Journal of Organic Chemistry, 2012 , # 17 p. 3261 - 3269

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Citation Number: 16

Abstract

Abstract Metallated porphyrin tweezers have demonstrated a remarkable ability to function as reporters of absolute stereochemistry for a number of different classes of organic molecules. Flexibility in binding, however, can result in an ensemble of different Exciton Coupled Circular Dichroism (ECCD) active conformations that could lead to variable results. Linker flexibility was found to be a key determinant of binding conformation. Experimental ...