Quinone–Annonaceous Acetogenins: Synthesis and Complex I Inhibition Studies of a New Class of Natural Product Hybrids

…, S Bäurle, T Friedrich, L Grubert, U Koert

Index: Hoppen, Sabine; Baeurle, Stefan; Koert, Ulrich Chemistry - A European Journal, 2000 , vol. 6, # 13 p. 2382 - 2396

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Citation Number: 39

Abstract

Abstract The natural product hybrids quinone–mucocin and quinone-squamocin D were synthesized. In these hybrids, the butenolide unit of the annonaceous acetogenins mucocin and squamocin D is exchanged for the quinone moiety of the natural complex I substrate