Regiocontrolled Synthesis of Ring??Fused Thieno [2, 3??c] pyrazoles through 1, 3??Dipolar Cycloaddition of Nitrile Imines with Sulfur??Based Acetylenes
JZ Chandanshive, BF Bonini, D Gentili…
Index: Chandanshive, Jay Zumbar; Bonini, Bianca Flavia; Gentili, Denis; Fochi, Mariafrancesca; Bernardi, Luca; Franchini, Mauro Comes European Journal of Organic Chemistry, 2010 , # 33 p. 6440 - 6447
Full Text: HTML
Citation Number: 23
Abstract
Abstract 1, 3-Dipolar cycloadditions of C-carboxymethyl-N-arylnitrile imines with substituted acetylenes bearing thiol or sulfone groups were studied. The sulfur controls the regiochemistry of the reaction, and this protocol was applied to the synthesis of ring-fused thieno [2, 3-c] pyrazoles.
Related Articles:
Novel disulfides with antitumour efficacy and specificity
[Griffiths, Rebecca; Wong, W. Wei-Lynn; Fletcher, Stephen P.; Penn, Linda Z.; Langler, Richard F. Australian Journal of Chemistry, 2005 , vol. 58, # 2 p. 128 - 136]
Inhibition of human cytomegalovirus protease N o with monocyclic β-lactams
[Deziel; Malenfant Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 11 p. 1437 - 1442]
Chemical evolution and the origin of life
[Groth Arkiv foer Kemi, vol. 9, # 1 p. 3 Chem. Zentralbl., 1924 , vol. 95, # I p. 1036]