Nucleophilic substitutions of unactivated vinyl halides with alkanethiolate anions in hexamethylphosphoramide
…, M Tingoli, D Chianelli, M Montanucci
Index: Tiecco, Marcello; Testaferri, Lorenzo; Tingoli, Marco; Chianelli, Donatella; Montanucci, Manuela Journal of Organic Chemistry, 1983 , vol. 48, # 25 p. 4795 - 4800
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Citation Number: 46
Abstract
The reactions of unactivated vinyl halides with the sodium salts of alkanethiols in HMPA gave vinyl alkyl sulfides in high yields. These reactions occur with complete retention of configuration. With di-, tri-, and tetrachloroethylenes all the chlorine atoms are substituted by alkylthio groups. By treatment with alkanethiolates the vinyl sulfides me dealkylated to give the sodium salts of the ene thiols. By reaction with sodium all the alkylthio groups present ...
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