Tetrahedron letters

Synthesis of indole-3-carboxamides via a haloform cleavage reaction of 3-trifluoroacetylindole with lithium dialkylamides

HL Hassinger, RM Soll, GW Gribble

Index: Hassinger, Heidi L.; Soll, Richard M.; Gribble, Gordon W. Tetrahedron Letters, 1998 , vol. 39, # 20 p. 3095 - 3098

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Citation Number: 8

Abstract

... Abstract. Reaction of 3-trifluoroacetylindole (4) with lithium dialkylamides affords the corresponding indole-3-carboxamides (5) in good to excellent yields. Reaction of 3-trifluoroacetylindole (4) with lithium dialkylamides affords the corresponding indole-3-carboxamides (5) in good to excellent yields. ... BD Palmer, GW Rewcastle, AM Thompson, M. Boyd, HDH Showalter, AD Sercel, DW Fry, AJ Kraker, WA Denny; J. Med. Chem., 38 (1995), pp. 58–67. ... 3. GW Gribble; ...