Structure-based drug design and potent anti-cancer activity of tricyclic 5: 7: 5-fused diimidazo [4, 5-d: 4′, 5′-f][1, 3] diazepines

A Kondaskar, S Kondaskar, JC Fishbein…

Index: Bioorganic and Medicinal Chemistry, , vol. 21, # 3 p. 618 - 631

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Citation Number: 11

Abstract

... Bioorganic & Medicinal Chemistry. ... Organic synthesis and medicinal chemistry; Diimidazo[4,5- d:4′,5′-f][1,3]diazepines; Anti-cancer activity; Lung, breast, prostate and ... 4 and 5 hDDX3 is of major medical importance due to its involvement in numerous cancers as well as viral ...