Thiourea inhibitors of herpes viruses. Part 1: bis-(aryl) thiourea inhibitors of CMV

JD Bloom, MJ DiGrandi, RG Dushin, KJ Curran…

Index: Bloom, Jonathan D.; DiGrandi, Martin J.; Dushin, Russell G.; Curran, Kevin J.; Ross, Adma A.; Norton, Emily B.; Terefenko, Eugene; Jones, Thomas R.; Feld, Boris; Lang, Stanley A. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 17 p. 2929 - 2932

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Citation Number: 29

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Bis-(aryl)thioureas were found to be potent and selective inhibitors of cytomegalovirus (CMV) in cultured HFF cells. Of these, the thiazole analogue 38 was investigated as a potential development candidate. ... Bis-(aryl)thioureas were found to be potent and selective ...