Digoxigenin-mono-und-bis-digitoxosid, zwei neue Glykoside der Digitalis lanata

E Haack, F Kaiser, H Spingler

Index: Haack et al. Naturwissenschaften, 1957 , vol. 44, p. 633

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Citation Number: 26

Abstract

Pyridine-N-oxide occupies an unique position in the quantum mechanical theory of organic reactivity. It undergoes both cationoid and anionoid substitution at the same positions, namely primarily at 4 and to a lesser extent at 2 position. The molecular orbital method of calculating electron density cannot correctly predict the reactivity of this compound, since it cammt predict maximum electrophilic and nucleophilic reactivity for the same position. ...