Microwave-assisted reductive cyclization of N-allyl 2-nitroanilines: a new approach to substituted 1, 2, 3, 4-tetrahydroquinoxalines
E Merisor, J Conrad, S Mika, U Beifuss
Index: Merisor, Elena; Conrad, Juergen; Mika, Sabine; Beifuss, Uwe Synlett, 2007 , # 13 p. 2033 - 2036
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Citation Number: 8
Abstract
Altogether there is a strong demand for new and efficient methods for the synthesis of the 1,2,3,4-tetrahydroquinoxaline skeleton. Recently, we discovered a new domino process that allows the transformation of allyl 2-nitrophenyl ethers into substituted 3,4-dihydro-2H-1,4-benzoxazines in a single synthetic operation. [11] Whether a new synthetic method is able to gain major importance will greatly depend on its scope and limitations. Here we report on the successful ...
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