New catalytic oxidation of trifluoromethyl carbinols by a ruthenium (II) complex

V Kesavan, D Bonnet-Delpon, JP Bégué, A Srikanth…

Index: Kesavan, Venkitasamy; Bonnet-Delpon, Daniele; Begue, Jean-Pierre; Srikanth, Abirami; Chandrasekaran, Srinivasan Tetrahedron Letters, 2000 , vol. 41, # 18 p. 3327 - 3330

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Citation Number: 30

Abstract

Fluorinated ketones, especially trifluoromethyl ketones, are of great interest because of their remarkable ability to function as enzyme inhibitors, 1 and because of their role as building blocks for trifluoromethyl heterocycles 2 and as monomers for novel polymeric materials. 3 Besides traditional methods involving the addition of Grignard or organo lithium reagents to trifluoroacetic acid, 4 other more recent methods such as the Wittig reaction with trifluoroacetamides, 5 ...