An Approach to Pyrazoline-Fused Chlorins by Dipolar [3+ 2]-Cycloaddition of Iminonitriles to meso-Tetrakis (pentafluorophenyl) porphyrin: Synthesis of New PDT …
P Wyrebek, S Ostrowski
Index: Wyrebek, Przemyslaw; Ostrowski, Stanislaw Bulletin of the Chemical Society of Japan, 2012 , vol. 85, # 10 p. 1167 - 1174,8
Full Text: HTML
Citation Number: 4
Abstract
meso-Tetrakis (pentafluorophenyl) porphyrin reacts at higher temperature with unstable iminonitriles (R–C≡ N+–N−–Ar), affording pyrazoline-fused chlorins, according to dipolar [3+ 2]-cycloaddition pathway. The respective iminonitriles were in situ generated from the corresponding functionalized α-halogenohydrazine derivatives by 1, 3-elimination of HX in the presence of base (NEt 3, DABCO). This method allows synthesis of very attractive ...
Related Articles:
[Hemming, Karl; Luheshi, Abdul-Bassett N.; Redhouse, Alan D.; Smalley, Robert K.; Thompson, J. Robin; et al. Tetrahedron, 1993 , vol. 49, # 20 p. 4383 - 4408]
[Patel, Himatkumar V.; Vyas, Kavita A.; Pandey, Sudhanshu P.; Fernandes, Peter S. Tetrahedron, 1996 , vol. 52, # 2 p. 661 - 668]