Synthesis and Characterization of Novel Cationic Lipids Derived from Thio Galactose
W Qiao, M Zhou, L Luo
Index: Qiao, Weihong; Zhou, Min; Luo, Limei Journal of Surfactants and Detergents, 2014 , vol. 17, # 2 p. 261 - 268
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Abstract
Abstract Two double chain cationic lipids QAS C n-2-S (n= 12, 14) derived from thio galactose and carbamate-linkage tertiary amine were synthesized and their structures were confirmed by MS, TOF-MS, 1 H NMR and 13 C NMR. The QAS C 12-2-S revealed superior surface activity compared with QAS C 14-2-S with lower CMC and γ CMC. Though Lipo C 12- 2-S displayed large average particle-size with high polydispersity, positive charged Lipo C ...
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