Imidazole pyrimidine amides as potent, orally bioavailable cyclin-dependent kinase inhibitors

CD Jones, DM Andrews, AJ Barker, K Blades…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 24 p. 6486 - 6489

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Citation Number: 22

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... Our own efforts in this area began with the imidazo[1,2-a]pyridine (5, A = CH) and imidazo[1,2-b]pyridazine (5, A = N) CDK inhibitors which were described in earlier letters (Fig. ...