Regioselective synthesis of methylated epigallocatechin gallate via nitrobenzenesulfonyl (Ns) protecting group

…, A Yoshida, T Furuta, T Wakimoto, T Akizawa…

Index: Aihara, Yoshiyuki; Yoshida, Atsusi; Furuta, Takumi; Wakimoto, Toshiyuki; Akizawa, Toshifumi; Konishi, Motomi; Kan, Toshiyuki Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 15 p. 4171 - 4174

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Citation Number: 29

Abstract

Regioselective synthesis of methylated epigallocatechin gallate from epigallocatechin was accomplished using a 2-nitrobenzenesulfonyl (Ns) group as a protecting group for phenols. This methodology provided several methylated catechins, which are naturally scarce catechin derivatives.