Iridium??Catalysed Allylic Substitution: Stereochemical Aspects and Isolation of IrIII Complexes Related to the Catalytic Cycle

B Bartels, C García??Yebra, F Rominger…

Index: Bartels, Bjoern; Garcia-Yebra, Cristina; Rominger, Frank; Helmchen, Guenter European Journal of Inorganic Chemistry, 2002 , # 10 p. 2569 - 2586

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Citation Number: 86

Abstract

Abstract Ir-catalysed allylic alkylations of enantiomerically enriched monosubstituted allylic acetates proceed with up to 87% retention of configuration using P (OPh) 3 as ligand. High regio-and enantioselectivity of up to 86% ee in asymmetric allylic alkylations of achiral or racemic substrates is achieved with monodentate phosphorus amidites as ligands. Lithium N-tosylbenzylamide was identified as a suitable nucleophile for allylic aminations. Of ...