Tetrahedron letters

Tris (3, 6-dioxaheptyl) amine: A superior complexing agent for dissolving metal reactions

AK Bose, P Mangiaracina

Index: Bose, Ajay K.; Mangiaracina, Pietro Tetrahedron Letters, 1987 , vol. 28, # 22 p. 2503 - 2506

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Citation Number: 12

Abstract

Abstract Commercially available tris (3, 6-dioxaheptyl) amine (TDA-1) is an effective phase transfer catalyst for reactions with sodium-potassium alloy in tetrahydrofuran. Deoxygenation of acetates, dehalogenation, and hydrolysis of tosylates and mesylates proceed in high yield. The use of a deuterated alcohol during deoxygenation reactions leads to site-specific deuteration.

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