Easy α-alkylation of ketones with alcohols through a hydrogen autotransfer process catalyzed by RuCl 2 (DMSO) 4
R Martínez, DJ Ramón, M Yus
Index: Martinez, Ricardo; Ramon, Diego J.; Yus, Miguel Tetrahedron, 2006 , vol. 62, # 38 p. 8988 - 9001
Full Text: HTML
Citation Number: 148
Abstract
The electrophilic α-alkylation of ketones with alcohols is accomplished by a hydrogen autotransfer process catalyzed by RuCl2 (DMSO) 4. The reaction can produce either simple alkylated ketones or α, β-unsaturated ketones just by choosing the appropriate starting ketones (methyl ketones or bicyclic methylenic ketones, respectively), as well as quinolines (by using 2-aminobenzyl alcohol derivatives) or the corresponding alcohol derivatives by ...
Related Articles:
Direct reductive amination versus hydrogenation of intermediates–A comparison
[Advanced Synthesis and Catalysis, , vol. 346, # 5 p. 561 - 565]
[Chen, Qihui; Yuan, Chengye Chemical Communications, 2008 , # 42 p. 5333 - 5335]
Direct reductive amination versus hydrogenation of intermediates–A comparison
[Advanced Synthesis and Catalysis, , vol. 346, # 5 p. 561 - 565]
[Bideau, Franck Le; Henique, Josette; Samuel, Edmond; Elschenbroich Chemical Communications, 1999 , # 15 p. 1397 - 1398]
Metal− Brønsted acid cooperative catalysis for asymmetric reductive amination
[Journal of the American Chemical Society, , vol. 131, p. 6967 - 6969]