Regiospecific synthesis of new fatty N-acyl trihalomethylated pyrazoline derivatives from fatty acid methyl esters (FAMEs)
…, MAP Martins, MGM D'Oca, LA Piovesan
Index: Beck, Paulo; Dos Santos, Juliane M.; Kuhn, Bruna L.; Moreira, Dayse N.; Flores, Alex F. C.; Martins, Marcos A. P.; D'Oca, Marcelo G. M.; Piovesan, Luciana A. Journal of the Brazilian Chemical Society, 2012 , vol. 23, # 11 p. 2122 - 2127
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Abstract
ABSTRACT A series of new fatty N-acyl trihalomethylated pyrazoline derivatives from fatty acid methyl esters was synthesized by the cyclocondensation of respective fatty hydrazides with 4-alkoxy-1, 1, 1-trialomethyl-3-alquen-2-ones. Efficient and regiospecific cyclizations catalyzed by BF 3· MeOH gave the desired products in good to excellent yields and at high purity.
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