Organic letters

Preparation of fully substituted anilines for the synthesis of functionalized indoles

AH Stoll, P Knochel

Index: Stoll, Armin H.; Knochel, Paul Organic Letters, 2008 , vol. 10, # 1 p. 113 - 116

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Citation Number: 70

Abstract

The indole skeleton is present in numerous bioactive natural products, pharmaceuticals, or agrochemicals, 1 and a range of synthetic methods has been developed 2 for the preparation of these heterocycles. Most methods rely on the incorporation of functionality prior to indole ring construction, 3 but directed metalations of indole scaffolds also provide access to functionalized indoles. 4 Recently, we have reported several methods for the preparation of ...