Advanced Synthesis & Catalysis

A Simple Synthetic Route to Enantiopure α??Hydroxy Ketone Derivatives by Asymmetric Hydrogenation

T Sun, X Zhang

Index: Sun, Tian; Zhang, Xumu Advanced Synthesis and Catalysis, 2012 , vol. 354, # 17 p. 3211 - 3215

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Citation Number: 7

Abstract

Abstract High enantioselectivities (up to 99% ee) have been observed for the catalytic asymmetric hydrogenation of the α-ketone enol acetates. DuanPhos has been proved to be the most effective ligand for this reaction. The high yield and enantioselectivity of the

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