Tetrahedron Letters

AgF/TFA-promoted highly efficient synthesis of α-haloketones from haloalkynes

ZW Chen, DN Ye, M Ye, ZG Zhou, SH Li, LX Liu

Index: Chen, Zheng-Wang; Ye, Dong-Nai; Ye, Min; Zhou, Zhong-Gao; Li, Shen-Huan; Liu, Liang-Xian Tetrahedron Letters, 2014 , vol. 55, # 7 p. 1373 - 1375

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Citation Number: 8

Abstract

Abstract A AgF/TFA-promoted highly efficient synthesis of a wide range of α-haloketones from haloalkynes is described. The reactions are conducted under convenient conditions and provide products in moderate to excellent yields, with broad substrate scope, including a variety of aromatic chloroalkynes and bromoalkynes.

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