Total synthesis of 6′-hydroxyjusticidin A
L Xiong, MG Bi, S Wu, YF Tong
Index: Xiong, Lu; Bi, Ming-Gang; Wu, Song; Tong, Yuan-Feng Journal of Asian Natural Products Research, 2012 , vol. 14, # 4 p. 322 - 326
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Citation Number: 3
Abstract
The first total synthesis of 6′-hydroxyjusticidin A, isolated from Justicia procumbens L. with good inhibitory activity against cancer cells, has been accomplished. The structure was confirmed by 1H NMR, 13C NMR, and HR-ESI-MS. The key steps involved a Diels–Alder cycloaddition reaction and a reduction in NaBH4.
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