Tetrahedron

Cyanide as a powerful catalyst for facile synthesis of benzofused heteroaromatic compounds via aerobic oxidation

YH Cho, CY Lee, CH Cheon

Index: Cho, Yeon-Ho; Lee, Chun-Young; Cheon, Cheol-Hong Tetrahedron, 2013 , vol. 69, # 32 p. 6565 - 6573

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Citation Number: 22

Abstract

Highly efficient synthesis of benzofused heteroaromatic compounds via aerobic oxidation catalyzed by cyanide anion has been developed. The Schiff bases derived from 2- aminophenol and aldehydes provided the corresponding benzoxazoles in high yields in the presence of a catalytic amount of cyanide in an open flask under ambient conditions without the use of any external metal co-oxidants and bases. Furthermore, we have developed a ...

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