Tetrahedron Letters

Ligand-free CuCl-catalyzed C–N bond formation in aqueous media

…, FY Zheng, YF Liang, ZY Cai, YS Feng, DQ Che

Index: Xu, Hua-Jian; Zheng, Fa-Yin; Liang, Yu-Feng; Cai, Zhen-Ya; Feng, Yi-Si; Che, Da-Qing Tetrahedron Letters, 2010 , vol. 51, # 4 p. 669 - 671

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Citation Number: 38

Abstract

We reported previously a method constructed C–N bond with Me 4 N + OH − as a base in organic solvent. 8 No product was observed with water as a solvent in this protocol. Inspired by this experimental result we wonder whether water can be used as a solvent by the alternative of base. Et 4 ...

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