An efficient approach to 2, 5-anhydro-glucitol-based 1′-homo-N-nucleoside mimetics
B Bhatt, RJ Thomson, M von Itzstein
Index: Bhatt, Beenu; Thomson, Robin J.; Von Itzstein, Mark Tetrahedron Letters, 2011 , vol. 52, # 21 p. 2741 - 2743
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Citation Number: 5
Abstract
Abstract This Letter describes an efficient synthesis of a range of 1′-homo-N-nucleoside mimetics with a series of 4-substituted 1, 2, 3-triazoles replacing the natural nucleobase. The synthesis of 6-O-monosulfated 1′-homo-N-nucleoside mimetic derivatives is also discussed.
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