Synthesis and antiproliferative activities of isoindigo and azaisoindigo derivatives
F Bouchikhi, F Anizon, P Moreau
Index: Bouchikhi, Fadoua; Anizon, Fabrice; Moreau, Pascale European Journal of Medicinal Chemistry, 2008 , vol. 43, # 4 p. 755 - 762
Full Text: HTML
Citation Number: 33
Abstract
In the course of structure–activity relationship studies, diversely substituted 1-(β-d- acetylatedglucopyranosyl) isoindigo derivatives were prepared from indolines. New 7′- azaisoindigo analogues were also synthesized by coupling a glycosylated isatine and a 7- azaindolin-2-one derivative. Compounds containing a 7′-azaisoindigo framework have never been described before. To get an insight into the substitution pattern required for the ...
Related Articles:
General synthesis of mono-, di-, and tri-acetylated indoles from indolin-2-ones
[Jha, Mukund; Chou, Ting-Yi; Blunt, Brian Tetrahedron, 2011 , vol. 67, # 5 p. 982 - 989]